SAN DIEGO (AP) " Jake Peavy pitched 8 1-3 strong innings, Adrian Gonzalez drove in three runs and Henry Blanco hit two home runs to lead the San Diego Padres to a 6-3 win over the San Francisco Giants on Saturday night.
Peavy (1-1) was sharper than in the season opener on Monday when he took the loss in a 4-1 defeat to the Los Angeles Dodgers. He allowed three runs on seven hits, struck out 10 and did not walk a batter.
Blanco tied his career high with two solo homers off Jonathan Sanchez (0-1), the second one leading off the fifth inning to break a 1-all tie. Gonzalez added a two-out, three-run double in the inning to knock Sanchez from the game and give the Padres a 5-1 lead.
The win gave the Padres a 4-2 record, matching their high mark for games over .500 from last season when it happened five times early on, the last coming on April 15 when San Diego was 8-6.
Peavy, who gave up four runs " three earned " in seven innings against the Dodgers " was more consistent as he worked quickly through the San Francisco lineup. Peavy retired the first nine batters before Randy Winn's leadoff double in the fourth.
He left after Fred Lewis' RBI double with one out in the ninth drove in Winn, who led off with an another double. Winn finished 3-for-4 with two runs scored.
Heath Bell got the final two outs for his third save.
Peavy's 10 strikeouts marked the 28th time he has had double-digit strikeouts.
Sanchez started strong by striking out five of his first six batters. He then allowed a homer to Blanco leading off the third.
In the fifth, Blanco hit his second homer of the season. Sanchez then issued a one-out walk to Peavy, gave up an infield single to Scott Hairston and loaded the bases with a walk to David Eckstein.
After getting Brian Giles on a short fly out, Gonzalez hit a ball into right-center field to drive in all three runs.
Sanchez allowed five runs and four hits, with seven strikeouts and two walks.
San Francisco scored its first run in the fourth after a mistake by Blanco.
After Winn led off with a double and moved to third on a single by Edgar Renteria, San Diego manager Bud Black called for a pitchout with Fred Lewis batting.
Renteria took off from first as Peavy delivered the pitch to Blanco. The catcher never looked over at Winn, but instead snapped a throw to Gonzalez at first base. When Blanco threw the ball, Winn took off for home and scored easily as Renteria got caught in a rundown before being tagged out.
The Giants scored in the seventh on Bengie Molina's sacrifice fly after Lewis' leadoff triple.
Notes: Although Peavy is 12-8 in his career against the Giants, he had lost five of eight starts coming in, including both starts last season. ... Blanco has homered twice in a game three times, the last coming on April 10, 2004, at Detroit. ... Gonzalez received his Gold Glove Award from last season. ... San Francisco, which lost the series opener on Friday night, took the season series with the Padres last year by going 13-5, including 7-2 at Petco Park. ... This series features the past two NL Cy Young Award winners with Peavy, the 2007 recipient, and last season's winner, Tim Lincecum, scheduled to start for San Francisco on Sunday.